Do you have psoriasis? Here are a few things to consider as natural remedies for this autoimmune condition.
Psoriasis is related to the body creating antibodies that attack your healthy tissues, whereas certain areas of skin are replaced every 3-5 days instead of the normal 28-30 day cycle.
This accelerated growth rate of certain skin cells then shows up on the skin as redness and/or dry flaking patches.
T-cell dysfunction, TH17 cells in particular, are the main culprits for inducing inflammation leading to the development of psoriasis, which is most notably triggered by an altered microbiome.
This is why several studies have shown an association between gut problems (IBD/IBS) and psoriasis, as well as a connection between joint pain and psoriasis.
Additionally, GAG (glycosaminoglycans) may be playing a critical role as it plays an important role in cell signaling, including regulation of growth, proliferation, promotion of cell adhesion, anticoagulation, and wound repair.
GAG also supports structural support to collagen and elastin.
People with psoriasis often find to have high levels of GAG in their urine, which is an indicator of excessive breakdown.
It’s important to also note that NAG (n-acetylglucosamine) is a precursor for GAG.
NAG can help with:
+ growth regulation
+ affects of cell growth
+ stimulate GAGs
+ support gut lining (improve leaky gut or mucosa lining)
+ immunosuppressive for t-cells
Clinical studies are showing NAGs ability to improve psoriasis, gut issues, and joint problems.
Additionally tips that help regulate T-cell function and boost immune health include:
+ Vitamin D3
+ Omega-3
+ Bile salts
Work with your PCP and/or integrative health practitioner for a plan that works best for you.
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Sources:
Method and composition for treating psoriasis
A pilot study of N-acetyl glucosamine
Bile acid metabolites control TH17 and Treg cell differentiation
